every time I save my changes, it popup the confirm dialog.
No, not possible to mute that one. If you find this feature really helpful I would suggest you to create a feature request issue.
If you want to implement this yourself you can modify the Grafana code. In combination with the feature request issue you’ve created you could create a pull request with your code changes. If lots of people upvotes the issue with a thumbs up emoji we’ll consider implementing/merging it.