Cross data center high available Grafana mimir setup

We are trying to setup grafana mimir on kubernetes with s3 object storage using its helm charts in microservices mode.
We are looking for suggested setup for grafana minor to enable high availability across data center. We know mimir provide HA within data enter by enabling copy of data in ingester.
Is this possible to have active active setup.
If yes, how to manage memcache across DC.
If not can we have active passive setup on same s3 storage.